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Molecular Ageing of Alpha- and Beta-Synucleins: Protein Damage and Repair Mechanisms
Abnormal α-synuclein aggregates are hallmarks of a number of neurodegenerative diseases. Alpha synuclein and β-synucleins are susceptible to post-translational modification as isoaspartate protein damage, which is regulated in vivo by the action of the repair enzyme protein L-isoaspartyl O-methyltra...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632608/ https://ncbi.nlm.nih.gov/pubmed/23630590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061442 |
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