Nelfinavir Inhibits Intra-Mitochondrial Calcium Influx and Protects Brain against Hypoxic-Ischemic Injury in Neonatal Mice

Nelfinavir (NLF), an antiretroviral agent, preserves mitochondrial membranes integrity and protects mature brain against ischemic injury in rodents. Our study demonstrates that in neonatal mice NLF significantly limits mitochondrial calcium influx, the event associated with protection of the brain a...

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Main Authors: Utkina-Sosunova, Irina V., Niatsetskaya, Zoya V., Sosunov, Sergey A., Ratner, Veniamin I., Matsiukevich, Dzmitry, Ten, Vadim S.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632564/
https://ncbi.nlm.nih.gov/pubmed/23614049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062448
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