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Secondary B Cell Receptor Diversification Is Necessary for T Cell Mediated Neuro-Inflammation during Experimental Autoimmune Encephalomyelitis

BACKGROUND: Clinical studies of B cell depletion in Multiple Sclerosis (MS) have revealed that B Lymphocytes are involved in the neuro-inflammatory process, yet it remains unclear how B cells can exert pro- and anti-inflammatory functions during MS. Experimental Autoimmune Encephalomyelitis (EAE) is...

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Detalhes bibliográficos
Main Authors: Galicia, Georgina, Boulianne, Bryant, Pikor, Natalia, Martin, Alberto, Gommerman, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632548/
https://ncbi.nlm.nih.gov/pubmed/23613859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061478
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