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A retrovirus expressing the 12S adenoviral E1A gene product can immortalize epithelial cells from a broad range of rat tissues.

An epithelial cell-transforming virus could be of great use, both in the culture of epithelial cell lines and in the study of carcinogenesis. Since the adenoviral E1A gene has been shown to partially transform some epithelial cells from primary rat cell cultures, we constructed retrovirus vectors co...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Cone, R D, Grodzicker, T, Jaramillo, M
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363246/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2966895/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.3.1036-1044.1988
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