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A retrovirus expressing the 12S adenoviral E1A gene product can immortalize epithelial cells from a broad range of rat tissues.

An epithelial cell-transforming virus could be of great use, both in the culture of epithelial cell lines and in the study of carcinogenesis. Since the adenoviral E1A gene has been shown to partially transform some epithelial cells from primary rat cell cultures, we constructed retrovirus vectors co...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Cone, R D, Grodzicker, T, Jaramillo, M
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363246/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2966895/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.3.1036-1044.1988
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