The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis

BACKGROUND AND PURPOSE: The non-psychotropic cannabinoid cannabichromene is known to activate the transient receptor potential ankyrin-type1 (TRPA1) and to inhibit endocannabinoid inactivation, both of which are involved in inflammatory processes. We examined here the effects of this phytocannabinoi...

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Detalhes bibliográficos
Main Authors: Romano, B, Borrelli, F, Fasolino, I, Capasso, R, Piscitelli, F, Cascio, MG, Pertwee, RG, Coppola, D, Vassallo, L, Orlando, P, Di Marzo, V, Izzo, AA
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632250/
https://ncbi.nlm.nih.gov/pubmed/23373571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12120
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