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The coupling between enhancer activity and hypomethylation of kappa immunoglobulin genes is developmentally regulated.

Previous studies have indicated that immunoglobulin enhancers are essential for establishing transcriptional competence but not for maintaining the activity of constitutively transcribed genes. To understand the basis for this developmental shift away from dependence on enhancer function, we have in...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Kelley, D E, Pollok, B A, Atchison, M L, Perry, R P
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363225/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3127693/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.2.930-937.1988
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