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The coupling between enhancer activity and hypomethylation of kappa immunoglobulin genes is developmentally regulated.

Previous studies have indicated that immunoglobulin enhancers are essential for establishing transcriptional competence but not for maintaining the activity of constitutively transcribed genes. To understand the basis for this developmental shift away from dependence on enhancer function, we have in...

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Detalhes bibliográficos
Main Authors: Kelley, D E, Pollok, B A, Atchison, M L, Perry, R P
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC363225/
https://ncbi.nlm.nih.gov/pubmed/3127693
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