The coupling between enhancer activity and hypomethylation of kappa immunoglobulin genes is developmentally regulated.
Previous studies have indicated that immunoglobulin enhancers are essential for establishing transcriptional competence but not for maintaining the activity of constitutively transcribed genes. To understand the basis for this developmental shift away from dependence on enhancer function, we have in...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363225/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3127693/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.2.930-937.1988 |
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