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Subchondral osteopenia and accelerated bone remodelling post-ovariectomy – a possible mechanism for subchondral microfractures in the aetiology of spontaneous osteonecrosis of the knee?

Osteopenia and subchondral microfractures are implicated in the aetiology of spontaneous osteonecrosis of the knee (SPONK). The ovine tibia shows significant alterations of the trabecular architecture within the subchondral bone of the medial tibial plateau post-ovariectomy (OVX), including reduced...

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Detalhes bibliográficos
Main Authors: Holland, JC, Brennan, O, Kennedy, OD, Rackard, S, O'Brien, FJ, Lee, TC
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632228/
https://ncbi.nlm.nih.gov/pubmed/23171138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joa.12007
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