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Induction of the Transcriptional Repressor ZBTB4 in Prostate Cancer Cells by Drug-induced Targeting of microRNA-17-92/106b-25 Clusters

Androgen-insensitive DU145 and PC3 human prostate cancer cells express high levels of specificity protein (Sp) transcription factors Sp1, Sp3 and Sp4, and treatment of cells with methyl 2-cyano-3,11-dioxo-18β-olean-1,12-dien-30-oate (CDODA-Me) inhibited cell growth and downregulated Sp1, Sp3 and Sp4...

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מידע ביבליוגרפי
Main Authors: Kim, KyoungHyun, Chadalapaka, Gayathri, Pathi, Satya S., Jin, Un-Ho, Lee, Ju-Seog, Park, Yun-Yong, Cho, Sung-Gook, Chintharlapalli, Sudhakar, Safe, Stephen
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632183/
https://ncbi.nlm.nih.gov/pubmed/22752225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0181
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