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Two distinct mechanisms of transcriptional control operate on c-myc during differentiation of HL60 cells.

We examined the mechanisms that control the downregulation of the c-myc mRNA during differentiation of HL60 cells. On treatment with dimethyl sulfoxide, HL60 cells downmodulated their steady-state c-myc message levels, ceased to proliferate, and underwent terminal differentiation. In nuclear run-on...

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Bibliografiske detaljer
Main Authors: Siebenlist, U, Bressler, P, Kelly, K
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC363218/
https://ncbi.nlm.nih.gov/pubmed/3162550
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