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Degradation of initiator tRNA(Met) by Xrn1/2 via its accumulation in the nucleus of heat-treated HeLa cells

Stress response mechanisms that modulate the dynamics of tRNA degradation and accumulation from the cytoplasm to the nucleus have been studied in yeast, the rat hepatoma and human cells. In the current study, we investigated tRNA degradation and accumulation in HeLa cells under various forms of stre...

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Detalhes bibliográficos
Main Authors: Watanabe, Kazunori, Miyagawa, Ryu, Tomikawa, Chie, Mizuno, Rie, Takahashi, Akihisa, Hori, Hiroyuki, Ijiri, Kenichi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632136/
https://ncbi.nlm.nih.gov/pubmed/23471000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt153
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