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PAR-2, LGL-1 and the CDC-42 GAP CHIN-1 act in distinct pathways to maintain polarity in the C. elegans embryo

In the one-cell C. elegans embryo, polarity is maintained by mutual antagonism between the anterior cortical proteins PAR-3, PKC-3, PAR-6 and CDC-42, and the posterior cortical proteins PAR-2 and LGL-1 on the posterior cortex. The mechanisms by which these proteins interact to maintain polarity are...

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Autors principals: Beatty, Alexander, Morton, Diane G., Kemphues, Kenneth
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631973/
https://ncbi.nlm.nih.gov/pubmed/23536568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.088310
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