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Interaction of PAR-6 with CDC-42 is required for maintenance but not establishment of PAR asymmetry in C. elegans

Caenorhabditis elegans embryonic polarity requires the asymmetrically distributed proteins PAR-3, PAR-6 and PKC-3. The rho family GTPase CDC-42 regulates the activities of these proteins in mammals, flies and worms. To clarify its mode of action in C. elegans we disrupted the interaction between PAR...

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Sonraí Bibleagrafaíochta
Main Authors: Aceto, Donato, Beers, Melissa, Kemphues, Kenneth J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148815/
https://ncbi.nlm.nih.gov/pubmed/16996049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.08.002
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