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Nuclear localization of human spermine oxidase isoforms – possible implications in drug response and disease etiology

The recent discovery of the direct oxidation of spermine via spermine oxidase (SMO) as a mechanism through which specific antitumor polyamine analogues exert their cytotoxic effects has fueled interest in the study of the polyamine catabolic pathway. A major byproduct of spermine oxidation is H(2)O(...

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Detalhes bibliográficos
Main Authors: Murray-Stewart, Tracy, Wang, Yanlin, Goodwin, Andrew, Hacker, Amy, Meeker, Alan, Casero, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631774/
https://ncbi.nlm.nih.gov/pubmed/18422650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2008.06419.x
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