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Dual fluorescent molecular substrates selectively report the activation, sustainability and reversibility of cellular PKB/Akt activity
Using a newly developed near-infrared (NIR) dye that fluoresces at two different wavelengths (dichromic fluorescence, DCF), we discovered a new fluorescent substrate for Akt, also known as protein kinase B, and a method to quantitatively report this enzyme's activity in real time. Upon insulin...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3631771/ https://ncbi.nlm.nih.gov/pubmed/23603888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01697 |
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