Dictyostelium Ric8 is a nonreceptor guanine exchange factor for heterotrimeric G proteins and is important for development and chemotaxis

Heterotrimeric G proteins couple external signals to the activation of intracellular signal transduction pathways. Agonist-stimulated guanine nucleotide exchange activity of G-protein-coupled receptors results in the exchange of G-protein-bound GDP to GTP and the dissociation and activation of the c...

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Bibliografiska uppgifter
Huvudupphovsmän: Kataria, Rama, Xu, Xuehua, Fusetti, Fabrizia, Keizer-Gunnink, Ineke, Jin, Tian, van Haastert, Peter J. M., Kortholt, Arjan
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2013
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631646/
https://ncbi.nlm.nih.gov/pubmed/23576747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301851110
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