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Cytochrome c causes pore formation in cardiolipin-containing membranes

The release of cytochrome c from mitochondria is a key signaling mechanism in apoptosis. Although extramitochondrial proteins are thought to initiate this release, the exact mechanisms remain unclear. Cytochrome c (cyt c) binds to and penetrates lipid structures containing the inner mitochondrial me...

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Detalhes bibliográficos
Main Authors: Bergstrom, Chris L., Beales, Paul A., Lv, Yang, Vanderlick, T. Kyle, Groves, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631622/
https://ncbi.nlm.nih.gov/pubmed/23576757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303819110
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