Herpes simplex virus-mediated human hypoxanthine-guanine phosphoribosyltransferase gene transfer into neuronal cells.

The virtually complete deficiency of the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT) results in a devastating neurological disease, Lesch-Nyhan syndrome. Transfer of the HPRT gene into fibroblasts and lymphoblasts in vitro and into hematopoietic cells in vivo has been...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Palella, T D, Silverman, L J, Schroll, C T, Homa, F L, Levine, M, Kelley, W N
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 1988
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363149/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2827006/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.1.457-460.1988
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