Herpes simplex virus-mediated human hypoxanthine-guanine phosphoribosyltransferase gene transfer into neuronal cells.

The virtually complete deficiency of the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT) results in a devastating neurological disease, Lesch-Nyhan syndrome. Transfer of the HPRT gene into fibroblasts and lymphoblasts in vitro and into hematopoietic cells in vivo has been...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Palella, T D, Silverman, L J, Schroll, C T, Homa, F L, Levine, M, Kelley, W N
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1988
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC363149/
https://ncbi.nlm.nih.gov/pubmed/2827006
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