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Optimization of designed armadillo repeat proteins by molecular dynamics simulations and NMR spectroscopy
A multidisciplinary approach based on molecular dynamics (MD) simulations using homology models, NMR spectroscopy, and a variety of biophysical techniques was used to efficiently improve the thermodynamic stability of armadillo repeat proteins (ArmRPs). ArmRPs can form the basis of modular peptide r...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3631359/ https://ncbi.nlm.nih.gov/pubmed/22767482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2117 |
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