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Ligand-induced μ opioid receptor internalization in enteric neurons following chronic treatment with the opiate fentanyl

Morphine differs from most opiates for its poor ability to internalize μ opioid receptors (μORs). However, chronic treatment with morphine produces adaptational changes at the dynamin level, which enhance the efficiency of acute morphine stimulation to promote μOR internalization in enteric neurons....

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Bibliographic Details
Main Authors: Anselmi, Laura, Jaramillo, Ingrid, Palacios, Michelle, Huynh, Jennifer, Sternini, Catia
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631303/
https://ncbi.nlm.nih.gov/pubmed/23553842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23214
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