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Ligand-induced μ opioid receptor internalization in enteric neurons following chronic treatment with the opiate fentanyl
Morphine differs from most opiates for its poor ability to internalize μ opioid receptors (μORs). However, chronic treatment with morphine produces adaptational changes at the dynamin level, which enhance the efficiency of acute morphine stimulation to promote μOR internalization in enteric neurons....
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Main Authors: | , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2013
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3631303/ https://ncbi.nlm.nih.gov/pubmed/23553842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23214 |
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