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Morphine induces μ opioid receptor endocytosis in guinea pig enteric neurons following prolonged receptor activation

BACKGROUND & AIMS: The μ opioid receptor (μOR) undergoes rapid endocytosis following acute stimulation with opioids and most opiates, but not with morphine. We investigated whether prolonged activation of μOR affects morphine’s ability to induce receptor endocytosis in enteric neurons. METHODS:...

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Detalhes bibliográficos
Main Authors: Patierno, Simona, Anselmi, Laura, Jaramillo, Ingrid, Scott, David, Garcia, Rachel, Sternini, Catia
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033567/
https://ncbi.nlm.nih.gov/pubmed/21070774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.11.005
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