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Tumor Necrosis Factor-α Promotes Survival of Opossum Kidney Cells via Cdc42-induced Phospholipase C-γ1 Activation and Actin Filament Redistribution

Although the renal proximal tubular epithelial cells are targeted in a variety of inflammatory diseases of the kidney, the signaling mechanism by which tumor necrosis factor (TNF)-α exerts its effects in these cells remains unclear. Here, we report that TNF-α elicits antiapoptotic effects in opossum...

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Auteurs principaux: Papakonstanti, Evangelia A., Stournaras, Christos
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC363127/
https://ncbi.nlm.nih.gov/pubmed/14699068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-07-0491
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