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Selective Activation of KCa3.1 and CRAC Channels by P(2)Y(2) Receptors Promotes Ca(2+) Signaling, Store Refilling and Migration of Rat Microglial Cells
Microglial activation involves Ca(2+) signaling, and numerous receptors can evoke elevation of intracellular Ca(2+). ATP released from damaged brain cells can activate ionotropic and metabotropic purinergic receptors, and act as a chemoattractant for microglia. Metabotropic P(2)Y receptors evoke a C...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3631179/ https://ncbi.nlm.nih.gov/pubmed/23620825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062345 |
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