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Persistence, Localization, and External Control of Transgene Expression After Single Injection of Adeno-Associated Virus into Injured Joints

A single intra-articular injection of adeno-associated virus (AAV) results in stable and controllable transgene expression in normal rat knees. Because undamaged joints are unlikely to require treatment, the study of AAV delivery in joint injury models is crucial to potential therapeutic application...

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Библиографические подробности
Главные авторы: Lee, Hannah H., O'Malley, Michael J., Friel, Nicole A., Payne, Karin A., Qiao, Chunping, Xiao, Xiao, Chu, Constance R.
Формат: Artigo
Язык:Inglês
Опубликовано: Mary Ann Liebert, Inc. 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631018/
https://ncbi.nlm.nih.gov/pubmed/23496155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.118
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