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Persistence, Localization, and External Control of Transgene Expression After Single Injection of Adeno-Associated Virus into Injured Joints

A single intra-articular injection of adeno-associated virus (AAV) results in stable and controllable transgene expression in normal rat knees. Because undamaged joints are unlikely to require treatment, the study of AAV delivery in joint injury models is crucial to potential therapeutic application...

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Detalhes bibliográficos
Main Authors: Lee, Hannah H., O'Malley, Michael J., Friel, Nicole A., Payne, Karin A., Qiao, Chunping, Xiao, Xiao, Chu, Constance R.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631018/
https://ncbi.nlm.nih.gov/pubmed/23496155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.118
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