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Depletion of Centromeric MCAK Leads to Chromosome Congression and Segregation Defects Due to Improper Kinetochore Attachments

The complex behavior of chromosomes during mitosis is accomplished by precise binding and highly regulated polymerization dynamics of kinetochore microtubules. Previous studies have implicated Kin Is, unique kinesins that depolymerize microtubules, in regulating chromosome positioning. We have chara...

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Detalhes bibliográficos
Main Authors: Kline-Smith, Susan L., Khodjakov, Alexey, Hergert, Polla, Walczak, Claire E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC363095/
https://ncbi.nlm.nih.gov/pubmed/14699064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-08-0581
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