‘Z(S)-MDR-TB' versus ‘Z(R)-MDR-TB': improving treatment of MDR-TB by identifying pyrazinamide susceptibility

Indispensable for shortening treatment of drug-susceptible tuberculosis (TB), pyrazinamide (PZA, Z) is also essential in the treatment of multidrug-resistant (MDR)-TB. While resistance to PZA in MDR-TB is associated with poor treatment outcome, bacillary susceptibility to PZA along with the use of f...

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Detalhes bibliográficos
Main Authors: Zhang, Ying, Chiu Chang, Kwok, Leung, Chi-Chiu, Wai Yew, Wing, Gicquel, Brigitte, Fallows, Dorothy, Kaplan, Gilla, Chaisson, Richard E, Zhang, Wenhong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630910/
https://ncbi.nlm.nih.gov/pubmed/26038418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emi.2012.18
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