Poly(ADP-ribose) Polymerase 1 Is a Key Regulator of Estrogen Receptor α-dependent Gene Transcription

Activation of nuclear receptor estrogen receptor α (ERα) exerts cardiovascular protective effects by modulating the expression of ERα target genes. However, the underlying mechanism remains unclear. PARP1 is a ubiquitous multifunctional nuclear enzyme. In this study, we examined the interplay betwee...

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Bibliographic Details
Main Authors: Zhang, Fengxiao, Wang, Yan, Wang, Lin, Luo, Xi, Huang, Kun, Wang, Cheng, Du, Meng, Liu, Fangmei, Luo, Ting, Huang, Dan, Huang, Kai
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630903/
https://ncbi.nlm.nih.gov/pubmed/23493398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.429134
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