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Differential Roles of the C and N Termini of Orai1 Protein in Interacting with Stromal Interaction Molecule 1 (STIM1) for Ca(2+) Release-activated Ca(2+) (CRAC) Channel Activation

The entry of extracellular Ca(2+), which is mediated by Ca(2+) release-activated Ca(2+) (CRAC) channels, is essential for T cell activation and the normal functioning of other immune cells. Although the molecular components of CRAC channels, the Orai1 pore-forming subunit and the STIM1-activating su...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zheng, Hongying, Zhou, Meng-Hua, Hu, Changlong, Kuo, Enoch, Peng, Xu, Hu, Junjie, Kuo, Lih, Zhang, Shenyuan L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630893/
https://ncbi.nlm.nih.gov/pubmed/23447534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.450254
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