Deleterious Cholesterol Hydroperoxide Trafficking in Steroidogenic Acute Regulatory (StAR) Protein-expressing MA-10 Leydig Cells: IMPLICATIONS FOR OXIDATIVE STRESS-IMPAIRED STEROIDOGENESIS

Steroidogenic acute regulatory (StAR) proteins in steroidogenic cells are implicated in the delivery of cholesterol (Ch) from internal or external sources to mitochondria (Mito) for initiation of steroid hormone synthesis. In this study, we tested the hypothesis that under oxidative stress, StAR-med...

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Detalhes bibliográficos
Main Authors: Korytowski, Witold, Pilat, Anna, Schmitt, Jared C., Girotti, Albert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630865/
https://ncbi.nlm.nih.gov/pubmed/23467407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.452151
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