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Human Genetic Disorders Caused by Mutations in Genes Encoding Biosynthetic Enzymes for Sulfated Glycosaminoglycans

A number of genetic disorders are caused by mutations in the genes encoding glycosyltransferases and sulfotransferases, enzymes responsible for the synthesis of sulfated glycosaminoglycan (GAG) side chains of proteoglycans, including chondroitin sulfate, dermatan sulfate, and heparan sulfate. The ph...

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Autori principali: Mizumoto, Shuji, Ikegawa, Shiro, Sugahara, Kazuyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630846/
https://ncbi.nlm.nih.gov/pubmed/23457301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R112.437038
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