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Positive Role of IQGAP1, an Effector of Rac1, in Actin-Meshwork Formation at Sites of Cell-Cell Contact

The small guanosine triphosphatase Rac1 is activated by E-cadherin-mediated cell-cell adhesion and is required for the accumulation of actin filaments, E-cadherin, and β-catenin at sites of cell-cell contact. However, the modes of activation and action of Rac1 remain to be clarified. We here found t...

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Autors principals: Noritake, Jun, Fukata, Masaki, Sato, Kazumasa, Nakagawa, Masato, Watanabe, Takashi, Izumi, Nanae, Wang, Shujie, Fukata, Yuko, Kaibuchi, Kozo
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC363077/
https://ncbi.nlm.nih.gov/pubmed/14699063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-08-0582
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