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Repeated supratherapeutic dosing of strontium ranelate over 15 days does not prolong QT(c) interval in healthy volunteers

AIMS: The study was performed to assess the safety of strontium ranelate in accordance with the ICH, E14 guidelines for QT/QT(c) studies. Its primary objective was to compare supratherapeutic repeated dosing of strontium ranelate (4 g day(−1) for 15 days) with placebo on the largest time-matched mea...

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Dettagli Bibliografici
Autori principali: Taubel, Jorg, Naseem, Asif, Wang, Duolao, Arezina, Radivoj, Lorch, Ulrike, Camm, A. John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630749/
https://ncbi.nlm.nih.gov/pubmed/22283848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04190.x
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