Design, Synthesis, and Functional Activity of Labeled CD1d Glycolipid Agonists

[Image: see text] Invariant natural killer T cells (iNKT cells) are restricted by CD1d molecules and activated upon CD1d-mediated presentation of glycolipids to T cell receptors (TCRs) located on the surface of the cell. Because the cytokine response profile is governed by the structure of the glyco...

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Autori principali: Jervis, Peter J., Polzella, Paolo, Wojno, Justyna, Jukes, John-Paul, Ghadbane, Hemza, Garcia Diaz, Yoel R., Besra, Gurdyal S., Cerundolo, Vincenzo, Cox, Liam R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2013
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630740/
https://ncbi.nlm.nih.gov/pubmed/23458425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300556e
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