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Extein Residues Play an Intimate Role in the Rate-Limiting Step of Protein Trans-Splicing

[Image: see text] Split inteins play an important role in modern protein semisynthesis techniques. These naturally occurring protein splicing domains can be used for in vitro and in vivo protein modification, peptide and protein cyclization, segmental isotopic labeling, and the construction of biose...

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Autors principals: Shah, Neel H., Eryilmaz, Ertan, Cowburn, David, Muir, Tom W.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2013
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630739/
https://ncbi.nlm.nih.gov/pubmed/23506399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja401015p
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