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DNA Target Enrichment and Background Depletion for Detection of Rare Sequences

We present an electrophoretic sample preparation method that is capable of both enriching a sample for multiple rare sequence targets from a large wild-type background with single nucleotide resolution, as well as depleting specific abundant sequences from a sample to allow sequencing of unknown rar...

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Autori principali: Pel, Joel, Wiggin, Matthew, Marziali, Andre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Association of Biomolecular Resource Facilities 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630692/
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