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Quality Control of DNA from Formalin-Fixed Paraffin-Embedded and Fresh-Frozen Tissues Prior to Targeted-Enrichment and Next Generation Sequencing

There are over 400 million formalin-fixed paraffin-embedded (FFPE) tissue samples archived in biobanks worldwide. These diseased and normal tissue collections are valuable resources for molecular genetic studies. However, the challenges of DNA extraction from FFPE tissues, including formaldehyde cro...

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Bibliografiske detaljer
Main Authors: Gassmann, Marcus, Ruefer, Andreas, Liu, Melissa, Salowsky, Ruediger
Format: Artigo
Sprog:Inglês
Udgivet: Association of Biomolecular Resource Facilities 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630617/
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