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Working Towards AutoTune for NanoESI Spray Optimization: Investigating the Key Parameters which affect Spray Stability on a 4000 QTRAP Interface

Establishing optimal spray conditions for nanoLC-MS is a key part of method development. Nano-ESI is dependent on a number of factors, including the effective voltage, specific dimensions of a given spray tip, effective flow rate and mobile phase composition. All of these parameters can be tightly c...

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Autors principals: Lee, Mike, Valaskovic, Gary, Berg, Amanda
Format: Artigo
Idioma:Inglês
Publicat: Association of Biomolecular Resource Facilities 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630665/
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