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Site-specific Labeling of Antibody N-glycans using a Click Chemistry-mediated Chemoenzymatic Approach

We present here a modular click chemistry-mediated method for the site-specific enzymatic labeling of essentially any antibody on the heavy chain N-linked glycans. While standard antibody labeling techniques can be cumbersome and tedious, with variable reproducibility and low yields, the described a...

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Autors principals: Aggeler, Robert, Berlier, Judie, Low, Quentin, Agnew, Brian
Format: Artigo
Idioma:Inglês
Publicat: Association of Biomolecular Resource Facilities 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630595/
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