Oncogenic B-Raf signaling in melanoma cells controls a network of microRNAs with combinatorial functions

Over two-thirds of melanomas have activating mutations in B-Raf, leading to constitutive activation of the B-Raf/MKK/ERK signaling pathway. The most prevalent mutation, B-RafV600E, promotes cancer cell behavior through mechanisms that are still incompletely defined. Here, we used a sensitive microar...

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Bibliographic Details
Main Authors: Couts, K L, Anderson, E M, Gross, M M, Sullivan, K, Ahn, N G
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630485/
https://ncbi.nlm.nih.gov/pubmed/22751131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.209
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