Llwytho...

A mammalian pre-mRNA 5′-end capping quality control mechanism and an unexpected link of capping to pre-mRNA processing

We recently reported that two homologous yeast proteins, Rai1 and Dxo1, function in a quality control mechanism to clear cells of incompletely 5′-end capped mRNAs. Here we report that their mammalian homolog, Dom3Z, possesses pyrophosphohydrolase, decapping and 5′-3′ exoribonuclease activities, and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jiao, Xinfu, Chang, Jeong Ho, Kilic, Turgay, Tong, Liang, Kiledjian, Megerditch
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630477/
https://ncbi.nlm.nih.gov/pubmed/23523372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.02.017
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