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Realizing the potential of the Actinium-225 radionuclide generator in targeted alpha-particle therapy applications

Alpha particle-emitting isotopes have been proposed as novel cytotoxic agents for augmenting targeted therapy. Properties of alpha particle radiation such as their limited range in tissue of a few cell diameters and their high linear energy transfer leading to dense radiation damage along each alpha...

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Autors principals: Miederer, Matthias, Scheinberg, David A., McDevitt, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630456/
https://ncbi.nlm.nih.gov/pubmed/18514364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2008.04.009
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