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Efficient one-step radiolabeling of monoclonal antibodies to high specific activity with Actinium-225 for alpha-particle radioimmunotherapy of cancer
Targeted alpha-particle radiation using the radioisotope (225)Actinium ((225)Ac) is a promising form of therapy for various types of cancer. Historical obstacles to the use of (225)Ac have been the difficulty in finding suitable chelators to stably attach it to targeting vehicles such as peptides an...
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| Publicado no: | J Nucl Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406251/ https://ncbi.nlm.nih.gov/pubmed/24982438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.114.138347 |
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