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Crystal Structures of E. coli Native MenH and Two Active Site Mutants

Recent revision of the biosynthetic pathway for menaquinone has led to the discovery of a previously unrecognized enzyme 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, also known as MenH. This enzyme has an α/β hydrolase fold with a catalytic triad comprising Ser86, His232, and Asp2...

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Detalhes bibliográficos
Main Authors: Johnston, Jodie M., Jiang, Ming, Guo, Zhihong, Baker, Edward N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630204/
https://ncbi.nlm.nih.gov/pubmed/23637813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061325
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