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Exploiting the high-resolution crystal structure of Staphylococcus aureus MenH to gain insight into enzyme activity
BACKGROUND: MenH (2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase) is a key enzyme in the biosynthesis of menaquinone, catalyzing an unusual 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate. RESULTS: The crystal structure of Staphyloco...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3097144/ https://ncbi.nlm.nih.gov/pubmed/21513522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-11-19 |
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