Protease-Activated Receptor (PAR)2, but Not PAR1, Is Involved in Collateral Formation and Anti-Inflammatory Monocyte Polarization in a Mouse Hind Limb Ischemia Model

AIMS: In collateral development (i.e. arteriogenesis), mononuclear cells are important and exist as a heterogeneous population consisting of pro-inflammatory and anti-inflammatory/repair-associated cells. Protease-activated receptor (PAR)1 and PAR2 are G-protein-coupled receptors that are both expre...

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Detalhes bibliográficos
Main Authors: van den Hengel, Lisa G., Hellingman, Alwine A., Nossent, Anne Yael, van Oeveren-Rietdijk, Annemarie M., de Vries, Margreet R., Spek, C. Arnold, van Zonneveld, Anton Jan, Reitsma, Pieter H., Hamming, Jaap F., de Boer, Hetty C., Versteeg, Henri H., Quax, Paul H. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630144/
https://ncbi.nlm.nih.gov/pubmed/23637930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061923
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