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TGF-β type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner
TGF-β superfamily members signal through a heteromeric receptor complex to regulate craniofacial development. TGF-β type II receptor appears to bind only TGF-β, whereas TGF-β type I receptor (ALK5) also binds to ligands in addition to TGF-β. Our previous work has shown that conditional inactivation...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3629921/ https://ncbi.nlm.nih.gov/pubmed/18572160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.03.045 |
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