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NKX2-1 Activation by SMAD2 Signaling After Definitive Endoderm Differentiation in Human Embryonic Stem Cell

Expression of NKX2-1 is required to specify definitive endoderm to respiratory endoderm. However, the transcriptional regulation of NKX2-1 is not fully understood. Here we demonstrate that aside from specifying undifferentiated human embryonic stem cell (hESC) to definitive endoderm, high concentrat...

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Detalhes bibliográficos
Main Authors: Li, Yong, Eggermont, Kristel, Vanslembrouck, Veerle, Verfaillie, Catherine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629846/
https://ncbi.nlm.nih.gov/pubmed/23259454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0620
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